Many testicular cancers contain both seminoma and non-seminoma cells. These mixed germ cell tumors are treated as non-seminomas. In this stage, the cancer has not spread outside the testicle, and your Because seminoma cells are very sensitive to radiation, low doses can. Patients with Stage 1 testicular cancer of non-seminoma type have a primary cancer that is limited to the testes and is curable in more than 95% of cases.

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Validation showed minor optimism in the c -statistic in the Cox regression models 0. Review provided by VeriMed Healthcare Network. Cancers that start in another organ and then spread metastasize to the testicle are called secondary testicular cancers.

Prediction of metastatic status in non-seminomatous testicular cancer.

We understand you carcionma be feeling overwhelmed with questions and concerns about your type of cancer and what it all means. Support Center Support Center. The c -statistic of the Testidular classification was 0. Non-dysgerminomatous germ cell tumor of testis Testicular non seminomatous germ cell tumor Testicular non-dysgerminomatous germ cell tumor Prevalence: Regression with missing X’s: These are most often in the lung or in the retroperitoneal lymph nodes. The IGCC classification can be viewed as implying that the risk factors are strongly dependent, that is, that there are interactions between risk factors.


The testicles are the male reproductive glands located in the scrotum. Treatment for testicular cancer is based mainly on the type and stage of the cancer. There are two sub-types of seminomas, and the classical typical seminomas are more likely to occur in men between ages of 30 and Disease progression occurred in patients, and patients died.

The information on this Web site tetsicular intended to help educate you about your treatment teeticular and to facilitate a mutual or shared decision-making process with your treating cancer physician.

The exact cause of testicular cancer is poorly understood. Developing a prognostic model in the presence of missing data: Treatment-induced anaemia and its potential clinical impact in patients receiving sequential high dose chemotherapy for metastatic testicular cancer. We’re here to help guide you through the process.

These tend to have a poor outlook because they usually don’t respond well to chemo or radiation therapy. A c -statistic was also calculated for both the three and five group classifications. Statistical Models in Epidemiology.

Stage I Non-Seminoma Testicular Cancer

Circumstances unique to your situation and prognostic factors of your cancer may ultimately influence how these general treatment principles are applied. For binary outcomes, the c -statistic is testixular to the area under the ROC curve Harrell et al This article has been cited by other articles in PMC.

Patients with clinical stage I non-seminoma may also elect to receive treatment with chemotherapy following orchiectomy and avoid a retroperitoneal lymph node dissection. As a splitting method, the exponential scaling method was used Therneau et al; LeBlanc and Crowley, Chat now Or call and ask an Oncology Information Specialist. When a model is developed and evaluated on the same data, the performance of the model is usually too optimistic. Prognostic groups In all classifications, three prognostic groups were identified using the estimated 5-year survival by sum score classification 5Rcombination of risk factors 5Ri or binary tree 5T.


Clinical trials for patients with stage I non-seminoma testicular cancer are limited to determining the initial extent of treatment necessary for optimal results and what the factors are that favor one approach over another.

What Is Testicular Cancer?

The cancer may look like a painless mass in the testes. The only way to diagnose testicular CIS is to have a biopsy. G Daugaard Rigshospitalet, Copenhagen. Symptoms in other parts of the body, such as the lungs, abdomen, pelvis, back, or brain, may also occur if the cancer has spread outside the testicles. Physicians have been surveyed to determine which therapy they would select. Summary and czrcinoma texts.